A Revolution in Formula Raising the bar in clean skincare backed by science and driven by results, Dr. Macrene’s revolutionary formulas nourish the skin with clean, active ingredients for visible restoration. USDA Certified Organically Grown Ingredients With our high-performance, plant-derived ingredients, skin transformation is possible. Clinically-tested solutions support a healthy, illuminated complexion and helps reduce the appearance of fine lines, sagging, and discoloration. A Perfect Blend of Science and Nature. Plant-derived, clean, vegan, silicone-free, paraben-free, phthalate-free, sulfate-free and fragrance-free, all-in-one products.