Stay Smart at the Holiday Inn Express Hotel Roseburg, Oregon. Our Roseburg hotel is strategically located on the bank of the South Umpqua River. Each of our 100 tastefully decorated guest rooms and suites feature a private balcony or patio offering a spectacular view of the South Umpqua River. The hotel located off I-5 exit 124 offers you easy access to the North Umpqua Highway, downtown Roseburg, wildlife watching, golfing and wine tasting. A few great attractions that are within a short traveling distance are: The Wildlife Safari, Crater Lake National Park, Myrtle Creek Golf Course, and scenic white-water rafting. We are located near the Roseburg VA Medical Center, Mercy Hospital and Roseburg Forest Products.